Stephen Hawking says:
I regard the brain as a computer which will stop working when its components fail. There is no heaven or afterlife for broken down computers; that is a fairy story for people afraid of the dark.
The only slight difference I have with this view is that there is some spark of identity (for lack of a better word) in me that I don’t think exists in a computer. That is, there’s something that makes me see out of my own eyes rather than someone else’s (or out of a computer’s eyes). I can’t even be sure that other people have it, though I assume they do.
Of course, without my brain, such a thing wouldn’t amount to much.